Zafatek Tablets 100mg

Generic name: Trelagliptin Succinate

Manufactured by: Teijin Pharma

Description

This medication inhibits DPP-4, an enzyme that breaks down incretin hormones responsible for regulating blood glucose levels. By blocking DPP-4, the medication helps stimulate insulin secretion when blood glucose levels are elevated, leading to improved blood glucose control. It is commonly prescribed for the management of type 2 diabetes mellitus.

Ingredients and dosage form

pale red oval tablet, major axis: 11.0 mm, minor axis: 5.6 mm, thickness: about 3.8 mm

Dosing schedule/Directions

Your dosing schedule should be determined by a doctor or healthcare professional. For adults, the typical dosage is 1 tablet (100 mg of trelagliptin) taken once a week on a consistent day. In patients with moderate to severe renal dysfunction, the dosage may be adjusted based on renal function. Always adhere strictly to your prescribed dosing instructions.

If you miss a dose, take it as soon as you remember and then continue with your regular weekly schedule. Do not take two doses at the same time. If you accidentally take more than the prescribed amount, contact your doctor or pharmacist immediately. Do not discontinue this medication unless directed by your doctor.

Warnings

Before starting this medication, inform your doctor and pharmacist if you have any of the following conditions:

- Allergic reactions to any medicines or foods (e.g., itching, rash)

- Ketosis, diabetic coma, precoma, type 1 diabetes mellitus, severe infections, renal disorders, pituitary abnormalities, or adrenal diseases

- Pre- or post-operative states

- Recent injuries

- A tendency to experience hypoglycemia

- Inadequate food intake, debility, or engaging in strenuous physical exercise

- Heavy alcohol consumption

- Recent laparotomy or bowel obstruction

- Dialysis

- Pregnancy or breastfeeding

- Use of other medicinal products (including over-the-counter medicines, dietary supplements, and prescription medicines, as interactions may affect the efficacy of this medication)

Precautions While Taking This Medication

- Follow dietary and exercise instructions carefully.

- If you experience hypoglycemic symptoms (e.g., hunger, cold sweat, pallor, fatigue, tremors, convulsions, decreased consciousness), consume carbohydrate-containing foods or sugar immediately.

- If taking this medication with an alpha-glucosidase inhibitor (e.g., acarbose, voglibose, miglitol), use glucose for hypoglycemia.

- This medication may cause acute pancreatitis (initial symptoms include severe abdominal pain and vomiting). Consult your doctor if these symptoms occur.

- As the medication is taken weekly and its effects persist after discontinuation, monitor for adverse reactions or changes in blood glucose levels. Report any abnormalities to your doctor or pharmacist.

- Be cautious of hypoglycemia when working at heights or driving. This may increase the risk of accidents.

- Periodically measure your blood glucose level as instructed by your doctor.

- Inform your family and those around you about your use of anti-diabetic medication.

Possible Adverse Reactions

Common adverse reactions include cold sweat, convulsions, decreased consciousness, blisters, rash, itching, vomiting, abdominal pain, and bloating. If you experience any of these symptoms, contact your doctor or pharmacist.

Rare but serious adverse reactions include:

- Hypoglycemia: Cold sweat, hunger, trembling of limbs

- Pemphigoid: Blisters, erosions, red rash

- Acute Pancreatitis: Nausea, abdominal pain, vomiting

- Intestinal Obstruction: Constipation, abdominal bloating, abdominal pain, nausea, vomiting

These symptoms do not cover all possible adverse reactions. Consult your doctor or pharmacist if you notice any unusual symptoms.

Storing Conditions

- Keep out of reach of children.

- Store at room temperature (between 1°C and 30°C), away from direct sunlight, heat, and moisture.

- Discard any unused medication properly. Do not store leftover medication. If you are unsure how to dispose of it, consult your pharmacy or medical institution for guidance.

- Do not share this medication with others.

Product specifications, appearance and package content are subject to change without prior notice.

Description of the medical drugs is not intended for prescribing treatment without the involvement of a physician.