Takecab Tablets 20mg

Generic name: Vonoprazan Fumarate

Manufactured by: Takeda Pharmaceutical Company

Description

This medicine inhibits the proton pump in a potassium ion-competitive manner to reduce gastric acid secretion in the stomach.

It is usually used to treat gastric/duodenal ulcer, reflux esophagitis and for suppression of recurrence of gastric/duodenal ulcer associated with low-dose aspirin or nonsteroidal anti-inflammatory drug medication.

Also this medicine inhibits the proton pump in a potassium ion-competitive manner and increases pH in the stomach to enhance antibacterial effects of antibacterial agents to be used concomitantly with two antibacterial agents in the treatment of Helicobacter pylori infection in gastric ulcer, duodenal ulcer, gastric MALT lymphoma, idiopathic thrombocytopenic purpura or after endoscopic therapy for early gastric cancer and Helicobacter pylori gastritis.

Ingredients and dosage form

faint red oval tablet, major axis: 11.2 mm, minor axis: 6.2 mm, thickness 3.9 mm

Dosing schedule/Directions

Your dosing schedule must be prescribed by your doctor ot healthcare professional.

Gastric/duodenal ulcer or reflux esophagitis: In general, for adults, take 1 tablet (20 mg of vonoprazan) at a time, once a day. Duration of taking the medicine is up to 8 weeks for gastric ulcer; 6 weeks for duodenal ulcer. To treat reflux esophagitis, in general, duration of taking the medicine is up to 4 weeks. If the effect is insufficient, the treatment may be continued for up to 8 weeks.

Maintenance therapy for repeatedly relapsing reflux esophagitis: In general, for adults, take 0.5 tablet (10 mg of vonoprazan) at a time, once a day. If the effect is insufficient, the dosage may be increased to 1 tablet (20 mg) at a time.

Suppression of recurrence of gastric/duodenal ulcers associated with low-dose aspirin or non-steroidal anti-inflammatory drug therapy: In general, for adults, take 0.5 tablet (10 mg of vonoprazan) at a time, once a day.

If you miss a dose, take the missed dose as soon as possible. In such instance, let more than 8 hours pass before the next dose. You should never take two doses at one time.

Concomitantly with two antibacterial agents in the treatment of Helicobacter pylori infection: In general, for adults, take 1 tablet (20 mg of vonoprazan) at a time, twice a day for 7 days. Take this medicine together with two antibacterial medicines. Strictly follow the instructions.

If you miss a dose, take the missed dose as soon as possible. If there is less than 5 hours to the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.

In any case, strictly follow the instructions.

If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.

Do not stop taking this medicine unless your doctor instructs you to do so.

Warnings

Before using this medicine, be sure to tell your doctor and pharmacist

If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.

If you have: liver/renal disorder.

If you are pregnant or breastfeeding.

If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Precautions while taking this medicine

- no records

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include constipation, diarrhea, taste abnormality, stomatitis, stomach discomfort, enlarged feeling of abdomen, nausea, rash and edema. If any of these symptoms occur, consult with your doctor or pharmacist.

The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.

ill feeling, diaphoresis, breathing difficulty, rash, facial edema, convulsion [shock, anaphylaxis]

general malaise, fever, shortness of breath, nose bleeding/subcutaneous bleeding [pancytopenia, agranulocytosis, decreased white blood cell, decreased platelets]

general malaise, loss of appetite, yellowing of the skin and the white of eyes [liver dysfunction]

fever, general malaise, rash/redness of the skin, eyes and oral cavity [toxic epidermal necrolysis, muco-cutaneo-ocular syndrome, erythema multiforme]

abdominal pain, frequent diarrhea [serious colitis]

The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storing Conditions

Keep out of reach of children. Store away from direct sunlight, heat and moisture.

Discard the remainder, do not store.

Product specifications, appearance and package content are subject to change without prior notice.

Description of the medical drugs is not intended for prescribing treatment without the involvement of a physician.