Suglat Tablets 50mg

Generic name: Ipragliflozin, L-Proline

Manufactured by: Astellas Pharma

Description

This medication inhibits SGLT2, a protein responsible for reabsorbing glucose in the kidneys. By blocking this protein, it reduces blood glucose levels by increasing the excretion of excess glucose in the urine. It is commonly used for the treatment of both type 1 and type 2 diabetes.

Ingredients and dosage form

pale purple tablet, diameter: approx. 8.6mm, thickness: approx. 3.9mm

Dosing schedule/Directions

Your dosing schedule should be prescribed by your doctor or healthcare professional.

- For Type 2 Diabetes: For adults, the typical starting dose is 1 tablet (50 mg of ipragliflozin) taken once daily, either before or after breakfast. If this dose is insufficient, it may be increased to 2 tablets (100 mg) once daily, with careful monitoring of the disease.

- For Type 1 Diabetes: For adults using insulin, start with 1 tablet (50 mg of ipragliflozin) once daily, before or after breakfast. If necessary, the dose may be increased to 2 tablets (100 mg) once daily, based on disease progression.

- For Severe Hepatic Dysfunction: If you have severe hepatic dysfunction, your doctor may start you on a lower dose.

If You Miss a Dose: Skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once.

If You Take Too Much: If you accidentally exceed the prescribed dose, consult your doctor or pharmacist immediately.

Discontinuation: Do not stop taking this medication unless directed by your doctor.

Warnings

Before starting this medication, inform your doctor and pharmacist

If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines or foods.

If you have: ketosis (nausea, sweet and sour smelling breath, deep and big breaths), infections, injury, pituitary gland dysfunction, abnormal adrenal gland function, irregular meals, inadequate food intake, urinary tract infection, genital infection or liver dysfunction.

If you are in a diabetic coma or a precoma stage; are perioperative, extremely underweight; are in a state of poor nutrition or starvation; are debilitated, a heavy drinker; are doing intense muscular exercise.

If you have renal dysfunction or are on dialysis.

If you are pregnant or breastfeeding.

If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Precautions while taking this medicine

Strictly follow the instructions on dietary/exercise therapy.

This medicine may cause hypoglycemic symptoms. Pay close attention when working at heights or operating dangerous machinery such as driving a car.

Take foods containing sugar or drink juice if any hypoglycemic symptoms occur. If you are taking in conjunction with α-glucosidase inhibitors (medicines which delay the uptake of glucose) and hypoglycemic symptoms develop, you must take in glucose.

This medicine may cause ketosis although your blood glucose level is nearly normal. The following patients should pay attention because they may easily fall into ketoacidosis: patients with type 1 diabetes mellitus, who reduced or stopped insulin formulation, who are subject to excessive carbohydrate intake restriction, who cannot eat sufficiently or with infection or dehydration. If you have type 1 diabetes mellitus, do not discontinue insulin injection.

Take a larger amount of water, since this medicine may cause dehydration. Do not stop taking water or decrease the amount of water on your own judgment.

Stop taking the medicine if you have repeated diarrhea/vomiting or cannot take food or water continuously due to decreased appetite.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include frequent urination, excessive urination, constipation, dry mouth, weight loss, cystitis and genital pruritus (itch). If any of these symptoms occur, consult with your doctor or pharmacist.

The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.

light headedness, lassitude, sweating, a sense of hunger, shivering of limbs[hypoglycemia]

chills, fever, flank pain, back pain, lower back pain, redness/swelling/pain in the genital area[pyelonephritis, necrotizing fasciitis of the vulva and perineum (Fournier's gangrene), sepsis]

thirst/dry mouth, excessive urination, dizziness/light headedness[dehydration]

nausea/vomiting, loss of appetite, abdominal pain, severe dry mouth, malaise[ketoacidosis]

facial pallor, cold sweat, dizziness on standing up[shock, anaphylaxis]

The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storing Conditions

- Keep out of reach of children.

- Store the medication away from direct sunlight, heat, and moisture.

- Discard any unused medication properly. Do not store leftover medicine.

Product specifications, appearance and package content are subject to change without prior notice.

Description of the medical drugs is not intended for prescribing treatment without the involvement of a physician.