REZALTAS COMBINATION TABLETS HD
Generic name: Olmesartan Medoxomil, Azelnidipine
Manufactured by: Daiichi Sankyo
Description
This medicine is a combination preparation of an angiotensin receptor blocker and a calcium antagonist. It lowers blood pressure by suppressing the vasoconstriction action of angiotensin II in vascular smooth muscles with angiotensin receptor blocker, and by dilating blood vessels with calcium antagonist.
It is usually used in the treatment of hypertension.

Ingredients and dosage form
one surface white, one surface white to yellowish white tablet (major axis: 14.2 mm, minor axis: 6.7 mm, thickness: approx. 5.3 mm)

Dosing schedule/Directions
Your dosing schedule must be written by a doctor or healthcare professional.
In general, for adults, take 1 tablet at a time, once a day after breakfast. Strictly follow the instructions.
The medicine contains 20 mg of olmesartan medoxomil and 16 mg of azelnidipine in 1 tablet.
If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
Do not stop taking this medicine unless your doctor instructs you to do so.

Warnings
Before taking this medicine be sure to tell your doctor and pharmacist.
If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines or foods.
If you have: renal artery stenosis, hyperkalemia, renal disorder, hepatic disorder, cerebrovascular disorder.
If you are on hemodialysis, or on a strict low-salt diet.
If you are pregnant, possibly pregnant or breastfeeding.
If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Precautions while taking this medicine
The medicine may cause dizziness or lightheadedness by decreasing blood pressure. Pay close attention when you work at heights, drive a car or operate dangerous machinery.
Do not drink grapefruit juice while you take the medicine because it may cause an excessive hypotensive response by increasing blood level of the medicine.

Possible adverse reactions to this medicine
The most commonly reported adverse reactions include dizziness and headache. If any of these symptoms occur, consult with your doctor or pharmacist.

The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.

breathing difficulty, swelling in the eyelids/lips/tongue, hives[angioedema]
decreased urine output, edema, headache [renal failure]
numbness in the limbs and lips, muscular weakness, paralysis in the limbs [hyperkalemia]
cold feeling, vomiting, faint, loss of consciousness [shock, faint, loss of consciousness]
general malaise, loss of appetite, yellowing in the skin/white of eyes [liver dysfunction, jaundice]
nasal bleeding, gums bleeding, subcutaneous bleeding [thrombocytopenia]
cold sweat, hungry feeling, lassitude [hypoglycemia]
dizziness, lightheadedness [atrioventricular block, sinus arrest, bradycardia]
muscle pain, lassitude, red-brown urine [rhabdomyolysis]
itch, general redness, blood pressure falling, decreased consciousness, palpitation[anaphylaxis]
nausea, severe stomachache, water-like stool[severe diarrhea]
fever, dry cough, respiratory distress, shortness of breath[interstitial pneumonia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storing Conditions
Keep out of the reach of children. Store away from light, heat and moisture.
Discard the remainder. Do not store the
Product specifications, appearance and package content are subject to change without prior notice.
Description of the medical drugs is not intended for prescribing treatment without the involvement of a physician.