PL Combination Granules

Generic name: Salicylamide, Acetaminophen, Anhydrous Caffeine, Promethazine Methylenedisalicylate

Manufactured by: Shionogi Pharma

Description

This medicine is a combination cold remedy as a nonpyrazolone drug.

It relieves cold symptoms such as fever, headache, joint pain, muscle ache, sore throat and runny and/or stuffy nose by 4 active ingredients including antipyretic analgesic and anti-histamine drug.

It is usually used for improvement or relief of the symptoms including nasal discharge, nasal obstruction, pharyngeal and laryngeal pain, headache, arthralgia, myalgia and fever, associated with common cold or inflammation in upper respiratory tract.

Before using this medicine, be sure to tell your doctor and pharmacist

If you have previously experienced any allergic reactions (itch, rash, etc. ) to any medicines.

If you are a patient with gastric or duodenal ulcer, aspirin-induced asthma or its history, glaucoma, obstructive diseases in urinary tract such as prostatic hypertrophy, or hepatic function disorder.

If you are pregnant or breastfeeding.

If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Precautions while taking this medicine

Do not drive a car or operate dangerous machinery because the medicine may induce drowsiness.

Alcohol (drinking) may induce or enhance the adverse reactions of the medicine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include sleepiness, thirst, gastrointestinal disorder, hyperventilation and rash. If any of these symptoms occur, consult with your doctor or pharmacist.

The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.

breathlessness, swelling around eyes and/or mouth (lips), hives [shock, anaphylaxis]

high fever, fluid-filled blister, inflammation in mucous membrane of eyes, mouth, etc., general redness [toxic epidermal necrolysis, mucocutaneous ocular syndrome, acute generalized exanthematous pustulosis, exfoliative dermatitis]

palpitation or shortness of breath, fever, sore throat, gum bleeding [aplastic anemia, pancytopenia, agranulocytosis, hemolytic anemia, thrombocytopenia]

dry cough, breathlessness, fever [interstitial pneumonia, eosinophilic pneumonia]

malaise, anorexia, yellowness in skin or in the white of eyes [fulminant hepatitis, hepatic function disorder, jaundice]

The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

Keep the medicine out of the reach of infants and children. Store it at room temperature (1 to 30 degrees Celsius) away from light and moisture.

Discard the remainder. Do not store them.

For further information, talk to your doctor or pharmacist.

Ingredients and dosage form

white granules for internal use

Dosing schedule/Directions

Your dosing schedule to be written by a healthcare professional

In general, for adults, take 1 g or 1 sachet (1 g) at a time, 4 times daily. The dosage may be adjusted according to your disease, age and symptoms. Strictly follow the instructions.

If you miss a dose, take it as soon as you remember. If it is close to your next dose, skip the missed dose. You should never take two doses at one time.

If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.

Do not stop taking this medicine unless your doctor instructs you to do so.

Product specifications, appearance and package content are subject to change without prior notice.

Description of the medical drugs is not intended for prescribing treatment without the involvement of a physician.