NOCBIN powder
Generic name: Disulfiram
Manufactured by: Tanabe Pharma
Description
This medication is used as part of a treatment plan for chronic alcoholism. It works by inhibiting the metabolism of acetaldehyde, a byproduct produced when alcohol is broken down in the liver. As a result, unpleasant physical reactions—such as nausea, flushing, and palpitations—occur when alcohol is consumed. These effects serve as a deterrent, helping patients avoid alcohol and support long-term sobriety.

Indication
This medicine is typically prescribed as an anti-alcohol therapy for individuals diagnosed with chronic alcohol dependence.

Ingredients and dosage form
white to yellowish white crystalline powder

Dosing schedule/Directions
Your exact dosing schedule should be determined and prescribed by your doctor or a qualified healthcare professional.

General Guidelines
For adults, the usual dosage ranges from 0.1 to 0.5 grams per day, taken in 1 to 3 divided doses. The appropriate dose and long-term maintenance regimen are determined based on your response to an alcohol challenge (drinking test).
The maintenance dose is typically 0.1 to 0.2 grams daily.
Your doctor may advise either daily administration or a cyclical schedule, such as 1 week on treatment followed by 1 week off.

Important Usage Notes
Missed Dose: Take the missed dose as soon as you remember. If it is close to the time of your next scheduled dose, skip the missed dose. Do not take two doses at once to make up for a missed one.
Overdose: In case of accidental overdose, contact your doctor or pharmacist immediately.
Treatment Interruption: Do not stop taking this medication unless explicitly directed by your doctor, even if symptoms improve.

Always follow your healthcare provider's instructions closely to ensure safe and effective treatment.

Warnings
Before Using This Medication
Inform your doctor and pharmacist if any of the following apply to you:
You have a history of allergic reactions (e.g., itching, rash, swelling) to medications or foods.
You suffer from any cardiac conditions, liver or kidney disorders, or respiratory diseases.
You are pregnant, may be pregnant, or are currently breastfeeding.
You are using any other medications, including prescription drugs, over-the-counter products, dietary supplements, or herbal remedies. Some combinations may result in drug interactions that affect the efficacy or safety of treatment.

Precautions While Taking This Medication
This medicine may impair concentration, reflexes, or alertness. Do not drive, operate heavy machinery, or perform hazardous tasks until you know how the drug affects you.
Avoid alcohol-containing foods (e.g., narazuke, a type of Japanese pickled vegetable made with sake lees), alcohol-based medications (such as medicated liquors), and cosmetic products containing alcohol (e.g., aftershave lotions).

Do not consume alcohol during treatment unless expressly advised by your physician.

Potential Adverse Reactions
Common side effects may include:
Skin rash
Liver dysfunction

If you experience any of these, consult your doctor or pharmacist promptly.

Rare but serious adverse reactions may begin with the following symptoms. If you notice any of these, stop taking the medication immediately and seek medical attention:
Confusion, disorientation (e.g., not knowing your location, time, or personal identity), memory loss, or difficulty thinking → [Possible cerebral disorder]
Persistent fatigue, loss of appetite, yellowing of the skin or eyes → [Signs of liver dysfunction or jaundice]

This list does not cover all possible side effects. If you experience any unusual or concerning symptoms, consult with your healthcare provider promptly.

Storing Conditions
Keep out of reach of children at all times.
Store in a cool, dry place, away from direct sunlight, heat, and moisture.
Do not store leftover medication. Discard any unused portion.
For proper disposal, consult your dispensing pharmacy or healthcare provider.
Do not share this medicine with others, even if they have similar symptoms.
Product specifications, appearance and package content are subject to change without prior notice.
Description of the medical drugs is not intended for prescribing treatment without the involvement of a physician.