MARIZEV Tablets 12.5mg

Generic name: Omarigliptin

Manufactured by: KISSEI PHARMACEUTICAL

Description

This medication inhibits the enzyme that breaks down incretin, a substance that helps stabilize blood glucose levels. By doing so, it enhances insulin secretion and lowers glucagon levels during hyperglycemia, thus improving blood glucose control. It is commonly prescribed for the treatment of type 2 diabetes.

Ingredients and dosage form

yellow, round, film coated tablet, diameter: 5.6 mm, thickness: 3.1 mm

Dosing schedule/Directions

Your dosing schedule should be prescribed by your doctor or healthcare professional.

- For General Use: Adults should take 2 tablets (25 mg of the active ingredient) once a week.

- For Severe or End-Stage Renal Dysfunction: Take 1 tablet (12.5 mg) once a week.

Follow these instructions carefully.

If You Miss a Dose: Take the missed dose as soon as you remember. Resume your regular weekly dosing schedule on the next planned day. Do not take two doses at once.

If You Take Too Much: If you accidentally exceed your prescribed dose, contact your doctor or pharmacist immediately.

Discontinuation: Do not stop taking this medication unless directed by your doctor.

Warnings

Before using this medicine inform your doctor and pharmacist if you:

- Have experienced any allergic reactions (e.g., itching, rash) to medicines or foods in the past.

- Have conditions such as ketosis, diabetic coma or precoma, type 1 diabetes, infections (if glycemic control with insulin is desired), injuries, renal dysfunction, pituitary or adrenal gland disorders, or insufficient diet.

- Are in a pre- or post-operative state or are debilitated.

- Engage in intense physical exercise or consume excessive amounts of alcohol.

- Are pregnant, breastfeeding, or taking any other medicinal products. (Some medications may interact, potentially altering their effects. Be cautious with over-the-counter medicines, dietary supplements, and other prescriptions.)

Precautions While Taking This Medicine

- Follow Diet and Exercise Instructions: Adhere strictly to the diet and exercise regimen prescribed by your doctor.

- Monitor for Hypoglycemia: The medication may cause hypoglycemic symptoms. Exercise caution when working at heights, driving, or operating dangerous machinery. If hypoglycemic symptoms occur, consume foods or drinks containing sugar (e.g., sugar, glucose, or a sugary drink). If you are also taking an alpha-glucosidase inhibitor (e.g., miglitol, acarbose), use glucose to treat hypoglycemia.

Possible Adverse Reactions

Common adverse reactions include hypoglycemia and constipation. Consult your doctor or pharmacist if you experience these symptoms.

Rare but Serious Symptoms

If you experience any of the following symptoms, stop taking the medication and seek medical attention immediately:

- Hypoglycemia: Chills, intense hunger, trembling of limbs

- Pemphigoid: Blisters, erosions, redness of the skin

- Acute Pancreatitis: Severe upper abdominal pain, lower back pain, nausea

- Intestinal Obstruction: Difficulty passing stool, stomach pain, abdominal bloating

These symptoms do not cover all possible adverse reactions. Contact your doctor or pharmacist if you notice any other concerning symptoms.

Storing Conditions

- Keep out of reach of children.

- Store the medication away from direct sunlight, heat, and moisture.

- Dispose of any unused medication properly. Do not keep leftover medicine.

Product specifications, appearance and package content are subject to change without prior notice.

Description of the medical drugs is not intended for prescribing treatment without the involvement of a physician.