Lenvima capsules 4mg
Generic name: Lenvatinib Mesilate
Manufactured by: Eisai
Description
This anticancer medication works by inhibiting key kinases involved in tumor growth and angiogenesis, thereby suppressing tumor proliferation and vascularization. It is typically prescribed for the treatment of the following conditions:

Radically unresectable thyroid carcinoma

Unresectable thymic carcinoma

Unresectable or metastatic renal cell carcinoma

Unresectable advanced or recurrent endometrial carcinoma that has progressed after prior cancer chemotherapy

This targeted therapy is indicated for patients with difficult-to-treat cancers where surgical options are not viable. Always follow your healthcare provider’s instructions for use.

Ingredients and dosage form
yellowish red capsule, full length: 14.3 mm

Dosing schedule/Directions
Your dosing schedule must be determined and supervised by your doctor or healthcare provider.

For adults with unresectable thyroid carcinoma or unresectable thymic carcinoma:
The recommended dose is 24 mg of the active ingredient once daily. Dosage adjustments may be made based on your clinical condition or tolerance.
Each capsule contains 4 mg of the active ingredient. Follow your healthcare provider’s instructions exactly.

For adults with unresectable or metastatic renal cell carcinoma or unresectable advanced/recurrent endometrial carcinoma (that has progressed following prior cancer chemotherapy):
The standard dose is 20 mg of the active ingredient once daily, used in combination with pembrolizumab (genetical recombination). Dose adjustments may be required depending on your response and side effects.
Each capsule contains 4 mg of the active ingredient. Always adhere strictly to the prescribed regimen.

Missed Dose:
If you forget to take a dose, take it as soon as you remember. However, if your next scheduled dose is near, skip the missed dose. Do not take two doses at once.

Overdose:
In the event of an accidental overdose, seek immediate medical advice from your doctor or pharmacist.

Important:
Do not discontinue this medication without your healthcare provider’s instruction.

Warnings
Before Using This Medicine

Before starting treatment with this medication, inform your doctor or pharmacist if any of the following apply to you:

You have a history of allergic reactions (such as rash, itching, or swelling) to medications or food.
You are pregnant, may be pregnant, or are currently breastfeeding.
You are using other medications, including prescription drugs, over-the-counter medicines, or dietary supplements. (This is important, as drug interactions may affect the safety and effectiveness of treatment.)

Precautions While Taking This Medicine

Regularly monitor your blood pressure, as this medication may cause hypertension.
This medicine may lead to fatigue, weakness (asthenia), or dizziness. Avoid operating heavy machinery or driving until you know how the medication affects you.
Women of childbearing potential should use highly effective contraception during treatment and for a defined period after stopping the medication, as advised by your healthcare provider.

Possible Adverse Reactions

Common side effects may include:
Hypertension (high blood pressure)
Hypothyroidism, with symptoms such as fatigue, puffy eyelids, cold intolerance, weight gain, sleepiness, constipation, hoarseness, or hair loss
Diarrhea, nausea, vomiting, or loss of appetite
Fatigue or weight loss
Proteinuria (cloudy urine)
Joint pain
Hand-foot syndrome: pain, redness, swelling, blistering, or skin peeling on palms and soles

If any of these symptoms occur, consult your doctor or pharmacist promptly.

Serious and Rare Adverse Reactions

The following symptoms may indicate a serious reaction. Stop taking the medicine immediately and seek medical attention if you experience:
Severely high blood pressure, fainting, or intense headache → [Possible sign of severe hypertension]
Severe chest, back, or abdominal pain → [Possible arterial dissection]
Anemia-related symptoms such as lightheadedness, dizziness, vomiting blood, black stools, or blood in urine → [Possible hemorrhage]
Confusion, chest pain, breathing difficulties, or headache → [Possible thromboembolism (arterial or venous)]
Irregular heartbeat, shortness of breath, palpitations → [Possible cardiac disorder]
Fever, dry cough, or difficulty breathing → [Possible interstitial lung disease]

Storing Conditions
Keep out of the reach of children to prevent accidental ingestion.

Store in a cool, dry place, away from direct sunlight, heat, and moisture.

Keep the capsules or tablets in their original press-through package (PTP) sheet until just before use to maintain product integrity.

Do not store leftover medication.
Discard any unused medicine properly. If you're unsure how to dispose of it, consult the pharmacy or medical facility where you received it.

Do not share this medication with others, even if they have similar symptoms. This medicine is prescribed based on individual health conditions and may not be safe for someone else.
Product specifications, appearance and package content are subject to change without prior notice.
Description of the medical drugs is not intended for prescribing treatment without the involvement of a physician.