Isodine Nodo Fresh is a Japanese throat spray (Class 3 OTC drug), clear-mint flavoured, for sore, swollen or irritated throat and hoarseness caused by throat inflammation; made by iNova Pharmaceuticals Japan and sold by Shionogi Healthcare.
1 mL contains povidone-iodine 4.5 mg (available iodine 0.45 mg).
Form: throat spray (solution) with a twin nozzle and cap, 25 mL.

Indications

Throat irritation, sore throat, swollen throat, throat discomfort and hoarseness caused by inflammation of the throat.

Ingredients & form

1mL of this product contains 4.5 mg of povidone iodine (available iodine 0.45 mg)
As additives, this product contains l-menthol, propylene glycol, D-sorbitol solution, glycerin, ethanol, flavor, and one other ingredient.

Dosage

Spray an appropriate amount onto the mucous membrane of the throat several times a day.
Precautions related to dosage:
- Strictly follow the directions.
- Point the nozzle at the affected part of the throat and spray 2–3 times while saying "aah" aloud (if you spray while breathing in, the liquid may get into the bronchi or lungs).
- Children should use it only under the guidance and supervision of a guardian.
- Use only for spraying the affected part of the throat; do not use on cuts or burns and do not take internally.
- Keep it out of the eyes. If it gets into the eyes, rinse at once with water or lukewarm water; if symptoms are severe, see an eye doctor.
A doctor's instructions prevail.

Warnings

Using this product may discolour dental materials containing silver (e.g. dentures).
Do not use (not following this may worsen current symptoms or make side effects more likely):
1. Do not use if you have ever had an allergic reaction to this product or any of its ingredients.
2. Do not use continuously for a long time.
Consult a doctor, pharmacist or registered seller before use if you:
- are pregnant or may be pregnant;
- are breast-feeding;
- have ever had an allergic reaction to a medicine or other substance;
- have severe sores (erosion) in the mouth;
- have been diagnosed with a thyroid disorder.
Stop use at once and consult a doctor, pharmacist or registered seller, taking this leaflet with you, if any of the following appear after use (possible side effects):
- skin: rash/redness, itching;
- mouth: roughness, stinging, burning sensation, irritation;
- digestive system: nausea;
- other: discomfort.
Rarely shock (anaphylaxis) may occur: soon after use, itching of the skin, hives, hoarseness, sneezing, itchy throat, breathing difficulty, palpitations, clouding of consciousness — see a doctor immediately.
If symptoms do not improve after 5–6 days of use, stop use and consult a doctor, pharmacist or registered seller, taking this leaflet with you.

Storage

(1) Seal tightly and store in a cool place avoiding direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to a different container. (It may lead to misuse or
alter the quality.)
(4) Pay attention to coloring when it comes into contact with clothes,
etc. Immediately wash it off with water in this case.
(5) Keep away from fire.
(6) Never prick the tip of the nozzle with a needle etc., because it is
very dangerous when the needle breaks.
(7) Please note that after the indicated content of the container has
been used up, some unusable residual volume will still remain in
the container.
(8) Do not use this product after the expiration date.