Description
This medicine inhibits the platelet aggregation induced by thromboxane A2 and inhibits the phosphodiesterase 3 (PDE3) activity of platelets and vascular smooth muscle, thus exerting an antiplatelet and vasodilative action and consequently improving blood flow. It is usually used to improve symptoms such as ulcer, pain and coldness attributed to chronic arterial occlusion, and to prevent recurrence of cerebral infarction.

Ingredients and dosage form
white tablet, diameter: 9.0 mm, thickness: 4.25 mm

Dosing schedule/Directions
Your dosing schedule must be prescribed by your doctor or a healthcare professional.
- In general, for adults, take 1 tablet (100 mg of active ingredient) at a time, twice daily. The dosage may be adjusted according to your disease, age or symptoms. Strictly follow the instructions.
- This medicine is orally disintegrating tablet. Take this medicine in either of the following ways:
(1) Take this medicine with water or warm water as you do an ordinary tablet.
(2) Moisten the tablet with saliva on your tongue and crush it lightly with your tongue, then swallow it with saliva. However, never take the tablet without water when you are in a lying position.
- If you miss a dose, take the dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
- If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
- Do not stop taking this medicine unless your doctor instructs you to do so.

Warnings
Before using this medicine, be sure to tell your doctor and/or pharmacist
- If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
- If you are bleeding (hemophilia, capillary fragility, hemoptysis, intracranial bleeding, bleeding from the gastrointestinal tract or urinary tract, bleeding in vitreous body, etc.).
- If you have congestive heart failure.
- If you are scheduled to undergo surgery or tooth extraction.
- If you are pregnant, possibly pregnant or breastfeeding.
- If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Precautions while taking this medicine
Do not take this medicine with grapefruit juice since it may enhance the effects of the medicine.
This medicine makes it more difficult for blood to clot. If your bleeding is prolonged or an injury involves a large area of your body, immediately visit a nearby hospital.
If you receive any treatment by another doctor, including dental treatment, tell the doctor or dentist that you are taking this medicine.

Possible adverse reactions to this medicine
The most commonly reported adverse reactions include headache, dull headache, tachycardia, abdominal pain, nausea or vomiting, dizziness, palpitation, diarrhea, rash, anemia, arrhythmia, eruption, itch, hives, photosensitivity and erythema. If any of these symptoms occur, consult with your doctor or pharmacist.

The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.

respiratory distress, general swelling, sudden onset of precordial chest pressure sensation or chest pain, pulse rate increased (more than 100 beats/min) [congestive heart failure, myocardial infarction, angina pectoris, ventricular tachycardia] headache, consciousness disorder, abdominal pain [bleeding (intracranial bleeding such as cerebral bleeding, pulmonary bleeding, gastrointestinal bleeding, nasal bleeding, fundal bleeding, etc.)]
headache, throat pain, muscular pain, high fever with chills and shivering [pancytopenia, agranulocytosis, thrombocytopenia]
fever, dry cough, respiratory distress [interstitial pneumonia]
general malaise, loss of appetite, yellowing in skin and white of eyes [hepatic dysfunction, jaundice]

The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storing Conditions
Keep out of the reach of children. Store away from direct sunlight and heat.
If there is a remainder, this is to be discarded. Do not store it.