Selara Tablets 25mg

Generic name: Eplerenone

Manufactured by: Viatris

Description

This medicine inhibits the binding of aldosterone to receptors which are involved in increased blood pressure, heart and vascular fibrosis, heart hypertrophy or ventricular arrhythmia, and consequently shows antihypertensive effects and anti-heart failure effects.

It is usually used to treat hypertension and chronic heart failure (for the patients receiving base treatment such as angiotension converting enzyme inhibitor or angiotensin II receptor antagonist, beta-blocker or diuretic).

Ingredients and dosage form

yellow tablet, diameter: 5.6 mm, thickness: 3.3 mm

Dosing schedule/Directions

Your dosing schedule must prescribed by your doctor or by a healthcare professional.

For treatment of hypertension: In general, for adults, start with 2 tablets (50 mg of the active ingredient) at a time, once a day. If it is not effective enough, the dosage may be increased up to 4 tablets (100 mg) per day. However, if you take this medicine in combination with other medicinal products that suppress its metabolism, the daily dosage may not exceed 1 tablet (25 mg) at a time, once a day.

For treatment of chronic heart failure: In general, for adults, start with 1 tablet (25 mg of the active ingredient) at a time, once a day. After 4 weeks from the start as a guide, the dosage may be increased to 2 tablets (50 mg) at a time, once a day according to the serum potassium level or conditions. However, if you have moderate renal dysfunction, start with 1 tablet (25 mg) at a time, once every other day. The maximum daily dose is 1 tablet (25 mg) at a time, once a day, but the dosage may be decreased or this medicine may be discontinued according to the serum potassium level or conditions. If you take this medicine in combination with other medicinal products that suppress its metabolism, the daily dosage may not exceed 1 tablet (25 mg) at a time, once a day.

In any case, strictly follow the instructions.

If you miss a dose and remember it within one day, take the missed dose when you remember. You should never take two doses at one time.

If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.

Do not stop taking this medicine unless your doctor instructs you to do so.

Warnings

Before using this medicine, be sure to tell your doctor and pharmacist

- If you have previously experienced any allergic reactions (itching, rash, etc.) to any medicines.

- If you have: hyperkalemia, diabetes mellitus with microalbuminuria or proteinuria, renal dysfunction or liver dysfunction.

- If you are pregnant or breastfeeding.

- If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Precautions while taking this medicine

Since this medicine may cause dizziness by declining blood pressure, pay close attention to operating dangerous machinery, such as driving a car or working at heights.

Avoid taking any health supplement containing St. John's wort (a kind of herb) with this medicine, since it may enhance the metabolism of this medicine and diminish medicinal effects.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include headache, dizziness, nausea, fatigue, hypotension, renal dysfunction, indigestion and muscle cramp. If any of these symptoms occur, consult with your doctor or pharmacist.

The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.

numbness of limbs or lips, muscle weakness, paralysis of limbs [hyperkalemia]

The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storing Conditions

Keep out of reach of children. Store away from direct sunlight, heat and moisture.

Discard the remainder, do not store.

Product specifications, appearance and package content are subject to change without prior notice.

Description of the medical drugs is not intended for prescribing treatment without the involvement of a physician.