Mexiletine Hydrochloride Capsules 100mg (Nichi-Iko)

Generic name: Mexiletine hydrochloride

Manufactured by: Nichi-Iko Pharmaceutical

Description

This medicine suppresses abnormal cardic excitation and restores disturbed pulse. It also inhibits spontaneous action potential occurrence of sensory nerve to suppress pain and numbness in limbs caused by diabetes mellitus.

It is usually used to treat tachyarrhythmia or to improve subjective symptoms (spontaneous pain and numbness) accompanied with diabetic neuropathy.

Ingredients and dosage form

pale yellowish red/white, major axis: 17.9 mm, minor axis: 6.1 mm

Dosing schedule/Directions

Your dosing schedule must be prescribed by your doctor or a healthcare professional

Tachyarrhythmia:

・In general, for adults, take 1 capsule (100 mg of the active ingredient) at a time, 3 times a day after meals. The dosage may be increased to 150 mg of the active ingredient at a time, 3 times a day, after meals if the effect is insufficient. The dosage may be adjusted according to age and symptoms of the patient.

Improvement of subjective symptoms (spontaneous pain and numbness) accompanied with diabetic neuropathy:

・In general, for adults, take 1 capsule (100 mg of the active ingredient) at a time, 3 times a day after meals. DO NOT exceed the daily maximum dosage, 3 capsules (300 mg).

・This preparation contains 100 mg of the active ingredient in a capsule. Strictly follow the instructions in any case.

・If you miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.

・If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.

・Do not stop taking this medicine unless your doctor instructs you to do so.

Warnings

Before using this medicine, be sure to tell your doctor and pharmacist

・If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.

・If you have conduction disorder and heart failure.

・If you are pregnant or breastfeeding.

・If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Precautions while taking this medicine

・This medicine may cause blank feeling, dizziness, etc. Avoid operating in potentially hazardous activities such as driving a car.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include nausea, abdominal pain, itch, generalized rash, fever, hives, erythema and erythema multiform. If any of these symptoms occur, consult with your doctor or pharmacist.

The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.

・erythema, blister/erosion, conjunctivitis [mucocutaneous-ocular syndrome, toxic epidermal necrolysis, erythroderma]

・rash, fever, lymph node swelling [hypersensitivity syndrome]

・dizziness, palpitation, fainting [ventricular tachycardia, atrioventricular block]

・decreased urine output, swelling of limbs and face, general malaise [renal failure]

・to see or hear something that is not really there, impaired mind, unable to recognize time or place [hallucination, confusion]

The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storing Conditions

・Keep out of the reach of children. Store away from heat, moisture and light.

・Discard the remainder, do not store. If you dispose of unused medicines, seek advice of your pharmacist about proper disposal of drugs.

Product specifications, appearance and package content are subject to change without prior notice.

Description of the medical drugs is not intended for prescribing treatment without the involvement of a physician.